(from a non copyrighted chart used in patient education)
BRCA1............Breast Cancer......Ovarian Cancer.........Other
By age 40.......20%.......................3%
By age 50.......30%.......................21%
By age 70........85%.......................40-50%
Lifetime...........85%.......................44%.............Colon 6%; Prostate 8%
Second
primary
cancer..............65%.......................16%
=========================================
BRCA2............Breast Cancer......Ovarian Cancer.........Other
By age 50.......28%.......................less than 1%
By age 70.......84%.......................27%
Life time........85%..............................male breast cancer 6%; Pancreatic cancer
General population
lifetime risk for breast cancer 12.5%
lifetime risk for ovarian cancer 1-2%
Sources of Data:
Breast and Ovarian Cancer Risks Due to Inherited Mutations in BRCA1 and BRCA2. Science, October 24, 2003; 302(5645): 643 - 646.(requires free registration to view full-text)
National Library of Medicine search
google-search on title
Wirk B. The Role of Ovarian Ablation in the Management of Breast Cancer. Breast Journal. 11(6):416-424, November/December 2005. (abstract and lists sources where full text can be purchased)
National Library of Medicine search
google-search on title and on Document number (PMD)